Gene expression and proteomics analysis from a NZB X SM F2 cross

Gene expression and proteomics analysis from a NZB X SM F2 cross

Description 

A previous QTL analysis of an NZB X SM F2 cross revelated QTL for multiple complex traits (see Stylianou et al., 2006). Here, candidate genes were explored for 9 of these QTL using information from gene expression (3x replication for NZB and SM strains performed on Affymetrix Mouse 430 v. 2 arrays), mass spectrometry (2x replication for NZB and SM strains using MALDI-TOF/TOF technology) and SNPs (138,000 SNPS from the Broad Institute database) from the inbred strains. Detailed protocols and results relating to this publication see Stylianou et al., 2008.

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